Any pet can develop behavior changes with aging. If your pet has a disease that decreases blood flow to the brain, such as heart disease, behavior changes may be more severe.
If your pet has liver disease, it may also have behavior changes because the liver controls the molecules circulating in the blood. When the liver cannot rid the body of toxic materials, the toxins enter the brain and alter behavior. This is most apparent one or two hours after eating.
Pets-fed diets low in antioxidants, phytonutrients (phyto=plant), and omega-3 fatty acids may experience the greatest deterioration in brain function.